• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 3.986

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_-_117229719	41.801	NM_134010	Nup107	nucleoporin 107
chr15_-_102181072	37.309	NM_153416	Aaas	achalasia, adrenocortical insufficiency, alacrimia
chr19_+_6085096	36.407	NM_026410	Cdca5	cell division cycle associated 5
chr16_-_18812064	35.458	NM_009862	Cdc45	cell division cycle 45 homolog (S. cerevisiae)
chr9_-_57492978	32.922	NM_007783	Csk	c-src tyrosine kinase
chr8_+_113580224	32.904	NM_028274	Exosc6	exosome component 6
chr4_+_108520389	30.223	NM_029571	Kti12	KTI12 homolog, chromatin associated (S. cerevisiae)
chr11_-_94515034	29.335		Eme1	essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr19_+_38129500	29.205	NM_028293 NM_001164362 NM_028760	Cep55	centrosomal protein 55
chr11_-_94515067	28.654	NM_177752	Eme1	essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr7_-_134185928	28.461	NM_145588	Kif22	kinesin family member 22
chr3_-_129534201	28.444	NM_026578	Gar1	GAR1 ribonucleoprotein homolog (yeast)
chr7_-_134185894	28.302		Kif22	kinesin family member 22
chr11_-_70051361	27.584	NM_001177601 NM_001177603 NM_001177606 NM_001177607 NM_026757 NM_145758	0610010K14Rik	RIKEN cDNA 0610010K14 gene
chr11_-_70051346	27.551		0610010K14Rik	RIKEN cDNA 0610010K14 gene
chr4_+_44313764	26.423	NM_010790	Melk	maternal embryonic leucine zipper kinase
chr3_+_137806411	26.411	NM_175389	Rg9mtd2	RNA (guanine-9-) methyltransferase domain containing 2
chr3_+_87734217	26.375	NM_177663	Isg20l2	interferon stimulated exonuclease gene 20-like 2
chr4_+_44313865	26.360		Melk	maternal embryonic leucine zipper kinase
chr2_+_5766079	25.764	NM_016918	Nudt5	nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr6_-_87788752	25.614	NM_133934	Isy1	ISY1 splicing factor homolog (S. cerevisiae)
chr4_-_122563299	25.531		Cap1	CAP, adenylate cyclase-associated protein 1 (yeast)
chr4_-_45333366	25.496	NM_025513	Exosc3	exosome component 3
chr6_+_117867280	24.522	NM_001166427	Hnrnpf	heterogeneous nuclear ribonucleoprotein F
chr6_-_100621086	24.504	NM_181590	Shq1	SHQ1 homolog (S. cerevisiae)
chr3_-_99966292	24.466	NM_175552	Wdr3	WD repeat domain 3
chr14_-_32308152	24.110	NM_025907	Mettl6	methyltransferase like 6
chr6_-_87788729	23.556		Isy1	ISY1 splicing factor homolog (S. cerevisiae)
chr4_-_122563074	23.337	NM_007598	Cap1	CAP, adenylate cyclase-associated protein 1 (yeast)
chr17_-_41071432	23.221	NM_031863	Cenpq	centromere protein Q
chr10_-_92773579	22.809		Elk3	ELK3, member of ETS oncogene family
chr11_-_70051081	22.713
chr4_+_124392019	22.676	NM_029157	Sf3a3	splicing factor 3a, subunit 3
chr6_+_112996326	22.383		Thumpd3	THUMP domain containing 3
chr4_-_123427465	22.314	NM_023423	Akirin1	akirin 1
chr6_+_145070255	21.924	NM_008511	Lrmp	lymphoid-restricted membrane protein
chr2_+_146838735	21.682	NM_011917	Xrn2	5'-3' exoribonuclease 2
chr17_+_34987323	21.623	NM_001045863 NM_001045864 NM_138580	Rdbp	RD RNA-binding protein
chr19_+_4154645	21.119	NM_016933	Ptprcap	protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr16_+_20717874	21.104	NM_145632	Polr2h	polymerase (RNA) II (DNA directed) polypeptide H
chr10_-_92773778	20.797	NM_013508	Elk3	ELK3, member of ETS oncogene family
chr2_+_71227270	20.742	NM_026115	Hat1	histone aminotransferase 1
chr6_+_119429620	20.735	NM_133940	Fbxl14	F-box and leucine-rich repeat protein 14
chr1_-_123464468	20.634	NM_025860	Ddx18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr8_+_72332573	20.506	NM_198101	Gmip	Gem-interacting protein
chr5_+_46061125	20.499	NM_019438	Ncapg	non-SMC condensin I complex, subunit G
chr16_+_20717922	20.444		Polr2h	polymerase (RNA) II (DNA directed) polypeptide H
chr10_+_110182506	20.408	NM_178609	E2f7	E2F transcription factor 7
chr3_-_129534032	20.171		Gar1	GAR1 ribonucleoprotein homolog (yeast)
chr4_-_118109775	20.108	NM_023223	Cdc20	cell division cycle 20 homolog (S. cerevisiae)
chr14_+_62950904	20.071	NM_026001	Rnaseh2b	ribonuclease H2, subunit B
chrX_+_46048180	20.051	NM_173376	Rbmx2	RNA binding motif protein, X-linked 2
chr3_-_57455612	19.771		Commd2	COMM domain containing 2
chr13_-_8995234	19.607	NM_027000	Gtpbp4	GTP binding protein 4
chr7_-_85992096	19.577	NM_029585	Det1	de-etiolated homolog 1 (Arabidopsis)
chr3_-_27052733	19.534	NM_001177625 NM_007900	Ect2	ect2 oncogene
chr11_-_101413104	19.434	NM_009764	Brca1	breast cancer 1
chr11_-_100956699	19.167	NM_008949	Psmc3ip	proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
chrX_-_35917684	19.021		Cul4b	cullin 4B
chr7_-_19857195	19.009	NM_009499	Vasp	vasodilator-stimulated phosphoprotein
chr4_-_118993081	18.860	NM_001110129 NM_001110130 NM_028677	Ppih	peptidyl prolyl isomerase H
chrX_-_35918177	18.760		Cul4b	cullin 4B
chr1_+_89110855	18.530		Eif4e2	eukaryotic translation initiation factor 4E member 2
chr12_-_70298068	18.476		1110034A24Rik	RIKEN cDNA 1110034A24 gene
chr6_+_17015159	18.414		Tes	testis derived transcript
chr3_-_89222140	18.377	NM_016904	Cks1b	CDC28 protein kinase 1b
chr8_-_109580546	18.162		Cog8	component of oligomeric golgi complex 8
chr1_+_120218417	18.087	NM_026472	Mki67ip	Mki67 (FHA domain) interacting nucleolar phosphoprotein
chr2_-_32568570	18.008		Cdk9	cyclin-dependent kinase 9 (CDC2-related kinase)
chr14_+_32308241	17.982	NM_028932	Eaf1	ELL associated factor 1
chr1_+_120218430	17.765		Mki67ip	Mki67 (FHA domain) interacting nucleolar phosphoprotein
chr12_+_79962662	17.735		Eif2s1	eukaryotic translation initiation factor 2, subunit 1 alpha
chrX_-_48371127	17.721	NM_172413	Rap2c	RAP2C, member of RAS oncogene family
chr4_+_155243643	17.710	NM_028020	Cpsf3l	cleavage and polyadenylation specific factor 3-like
chr19_+_47165231	17.634	NM_011053	Pdcd11	programmed cell death 11
chr8_-_127386864	17.621	NM_025615	2810004N23Rik	RIKEN cDNA 2810004N23 gene
chr2_-_26758315	17.613	NM_009298	Surf6	surfeit gene 6
chr1_+_173319048	17.506	NM_001005508	Arhgap30	Rho GTPase activating protein 30
chr7_+_134439804	17.453	NM_008400	Itgal	integrin alpha L
chr6_+_17015148	17.447	NM_207176	Tes	testis derived transcript
chr14_-_121778143	17.354		Stk24	serine/threonine kinase 24 (STE20 homolog, yeast)
chr7_-_88046106	17.303	NM_028026	Wdr73	WD repeat domain 73
chrX_-_99352341	17.290	NM_146235	Ercc6l	excision repair cross-complementing rodent repair deficiency complementation group 6 - like
chr6_+_120314116	17.275	NM_145997	Kdm5a	lysine (K)-specific demethylase 5A
chr16_-_23127779	17.240	NM_145480	Rfc4	replication factor C (activator 1) 4
chr7_-_133935662	17.219		Ppp4c	protein phosphatase 4, catalytic subunit
chr8_-_109580588	16.981	NM_139229	Cog8	component of oligomeric golgi complex 8
chr8_-_126544907	16.969		Taf5l	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr2_+_90519527	16.946		Nup160	nucleoporin 160
chr4_+_124527985	16.907	NM_153566	Yrdc	yrdC domain containing (E.coli)
chr7_-_133935952	16.898	NM_019674	Ppp4c	protein phosphatase 4, catalytic subunit
chr16_-_30587549	16.800	NM_178069	Lsg1	large subunit GTPase 1 homolog (S. cerevisiae)
chr4_-_59562054	16.717	NM_144904 NM_178164	Rod1	ROD1 regulator of differentiation 1 (S. pombe)
chr7_+_109044853	16.686	NM_027532	3200002M19Rik	RIKEN cDNA 3200002M19 gene
chr18_+_35020867	16.670		Egr1	early growth response 1
chr17_+_34727032	16.653		Gpsm3	G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr3_+_79395280	16.635	NM_026352	Ppid	peptidylprolyl isomerase D (cyclophilin D)
chr9_-_57493393	16.586		Csk	c-src tyrosine kinase
chr16_-_22163035	16.574		Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2
chr11_-_79337178	16.564		Evi2b	ecotropic viral integration site 2b
chr17_-_36053309	16.500	NM_025878	Mrps18b	mitochondrial ribosomal protein S18B
chr19_-_5661634	16.356		Sipa1	signal-induced proliferation associated gene 1
chr19_+_47165272	16.351		Pdcd11	programmed cell death 11
chr12_-_32893074	16.226	NM_001146201 NM_020272 NM_001146200	Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr6_-_88396477	16.223	NM_023060	Eefsec	eukaryotic elongation factor, selenocysteine-tRNA-specific
chr18_+_32996878	16.149	NM_001110015 NM_001110016 NM_144863	Wdr36	WD repeat domain 36
chr11_+_4795308	16.122	NM_172438	Thoc5	THO complex 5
chr14_+_76510684	16.077	NM_013745	Nufip1	nuclear fragile X mental retardation protein interacting protein 1
chr11_+_32433265	15.973	NM_009288	Stk10	serine/threonine kinase 10
chr2_-_31939210	15.962	NM_175511	Fam78a	family with sequence similarity 78, member A
chr18_-_35091570	15.950	NM_144866	Etf1	eukaryotic translation termination factor 1
chr15_-_97923632	15.870	NM_144851	Senp1	SUMO1/sentrin specific peptidase 1
chr10_-_77647837	15.866	NM_029546	Pwp2	PWP2 periodic tryptophan protein homolog (yeast)
chr17_+_34046356	15.784	NM_007829	Daxx	Fas death domain-associated protein
chr14_-_121778399	15.782	NM_145465	Stk24	serine/threonine kinase 24 (STE20 homolog, yeast)
chr16_+_93832365	15.725	NM_001045529	Morc3	microrchidia 3
chr10_-_39966784	15.646	NM_001042556 NM_023323	Rpf2	ribosome production factor 2 homolog (S. cerevisiae)
chr7_+_29581002	15.604		Rinl	Ras and Rab interactor-like
chr15_-_99305127	15.602	NM_029236	Bcdin3d	BCDIN3 domain containing
chr15_-_102062331	15.597	NM_013566	Itgb7	integrin beta 7
chr11_-_74991810	15.561
chr4_-_116300068	15.527	NM_001081475	Nasp	nuclear autoantigenic sperm protein (histone-binding)
chr6_+_88415396	15.480	NM_019685	Ruvbl1	RuvB-like protein 1
chr11_+_74711572	15.319	NM_177325	Tsr1	TSR1, 20S rRNA accumulation, homolog (yeast)
chr1_-_33726582	15.236	NM_008922	Prim2	DNA primase, p58 subunit
chr3_+_79395257	15.214		Ppid	peptidylprolyl isomerase D (cyclophilin D)
chr4_-_63064369	15.170	NM_001045514	Akna	AT-hook transcription factor
chr13_+_100894802	14.962	NM_011420	Smn1	survival motor neuron 1
chr9_+_108362848	14.944	NM_133744	Ccdc71	coiled-coil domain containing 71
chr19_-_53465036	14.908	NM_172429	Smndc1	survival motor neuron domain containing 1
chr7_-_19857121	14.799		Vasp	vasodilator-stimulated phosphoprotein
chr8_-_126545208	14.779	NM_133966	Taf5l	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr12_+_25183430	14.716	NM_020614	Taf1b	TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
chr9_+_20692618	14.705	NM_145610	Ppan	peter pan homolog (Drosophila)
chrX_+_45610055	14.648	NM_028276	Utp14a	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
chr19_+_5366812	14.568	NM_027236	Eif1ad	eukaryotic translation initiation factor 1A domain containing
chr7_+_25155455	14.462		Kcnn4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr14_-_27489331	14.427	NM_178668	Pde12	phosphodiesterase 12
chr16_-_19983049	14.385	NM_183390	Klhl6	kelch-like 6 (Drosophila)
chr17_-_24210437	14.371	NM_027008	Kctd5	potassium channel tetramerisation domain containing 5
chr14_-_27489119	14.369		Pde12	phosphodiesterase 12
chr14_+_32308287	14.364		Eaf1	ELL associated factor 1
chr7_-_132634942	14.247		Nsmce1	non-SMC element 1 homolog (S. cerevisiae)
chr8_+_86239131	14.221		Ddx39	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr11_-_70468019	14.200		Pfn1	profilin 1
chr17_-_24210402	14.196		Kctd5	potassium channel tetramerisation domain containing 5
chr14_-_64162744	14.181	NM_177594	Mtmr9	myotubularin related protein 9
chr19_+_9016466	14.169		Mta2	metastasis-associated gene family, member 2
chr17_+_36053855	14.113	NM_175934	Ppp1r10	protein phosphatase 1, regulatory subunit 10
chr1_-_171461510	14.109	NM_023284	Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr7_-_29164215	14.068	NM_011756	Zfp36	zinc finger protein 36
chr10_-_79783221	14.015	NM_025521	2310011J03Rik	RIKEN cDNA 2310011J03 gene
chr1_+_66747396	14.005	NM_025683	Rpe	ribulose-5-phosphate-3-epimerase
chr16_-_22163264	13.993	NM_183029	Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2
chr19_-_5366600	13.978	NM_011793	Banf1	barrier to autointegration factor 1
chr9_-_114690887	13.928	NM_133978	Cmtm7	CKLF-like MARVEL transmembrane domain containing 7
chr14_-_64162810	13.854		Mtmr9	myotubularin related protein 9
chr2_+_166840778	13.853	NM_153065	Ddx27	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr4_-_40704838	13.849		Smu1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
chr15_-_63829523	13.843		Fam49b	family with sequence similarity 49, member B
chr10_+_74980789	13.819		Snrpd3	small nuclear ribonucleoprotein D3
chr5_+_97426665	13.788	NM_080708	Bmp2k	BMP2 inducible kinase
chr4_-_40704878	13.766		Smu1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
chr6_+_120314442	13.750		Kdm5a	lysine (K)-specific demethylase 5A
chr14_+_70499874	13.744	NM_021328	Bin3	bridging integrator 3
chr7_+_29581063	13.733		Rinl	Ras and Rab interactor-like
chr5_+_147043131	13.646	NM_153599	Cdk8	cyclin-dependent kinase 8
chr8_-_86628606	13.573	NM_172502	Dcaf15	DDB1 and CUL4 associated factor 15
chr14_-_52816830	13.562	NM_033618	Supt16h	suppressor of Ty 16 homolog (S. cerevisiae)
chr8_+_86239094	13.553	NM_197982	Ddx39	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr19_+_9016335	13.543	NM_011842	Mta2	metastasis-associated gene family, member 2
chr12_+_79962998	13.532	NM_026114	Eif2s1	eukaryotic translation initiation factor 2, subunit 1 alpha
chr9_-_70269326	13.516	NM_007630	Ccnb2	cyclin B2
chr7_-_109398578	13.509	NM_019566	Rhog	ras homolog gene family, member G
chrX_+_71675016	13.468	NM_010547 NM_178590	Ikbkg	inhibitor of kappaB kinase gamma
chr11_-_79337251	13.393	NM_001077496	Evi2b	ecotropic viral integration site 2b
chr2_-_120229789	13.375	NM_001110496 NM_001110497 NM_173734	Tmem87a	transmembrane protein 87A
chr19_-_9973901	13.274	NM_016692	Incenp	inner centromere protein
chr12_+_4599810	13.204	NM_001198968 NM_001198969 NM_011365	Itsn2	intersectin 2
chr5_-_30399962	13.182	NM_021288	Tyms	thymidylate synthase
chr7_+_126937608	13.137	NM_028129 NM_001004187	2610020H08Rik	RIKEN cDNA 2610020H08 gene
chr11_-_53113682	13.110		Hspa4	heat shock protein 4
chr5_+_34001199	13.017		Tacc3	transforming, acidic coiled-coil containing protein 3
chr17_+_3114963	13.010	NM_134123	Scaf8	SR-related CTD-associated factor 8
chr2_+_76208040	12.946	NM_153405	Rbm45	RNA binding motif protein 45
chr2_+_130250035	12.871	NM_030559	Vps16	vacuolar protein sorting 16 (yeast)
chr17_-_74715708	12.838	NM_001146222 NM_001146223	Dpy30	dpy-30 homolog (C. elegans)
chr8_-_42502362	12.834	NM_013522	Frg1	FSHD region gene 1
chr8_+_112302530	12.828	NM_009677	Ap1g1	adaptor protein complex AP-1, gamma 1 subunit
chr3_-_135354151	12.818		Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
chr9_-_65427840	12.814	NM_153119	Plekho2	pleckstrin homology domain containing, family O member 2
chr19_+_5366979	12.773		Eif1ad	eukaryotic translation initiation factor 1A domain containing
chr5_-_136611846	12.769	NM_027891	Lrwd1	leucine-rich repeats and WD repeat domain containing 1
chr17_-_29400874	12.669	NM_026845	Ppil1	peptidylprolyl isomerase (cyclophilin)-like 1
chr13_+_17787239	12.595	NM_025479	2810021B07Rik	RIKEN cDNA 2810021B07 gene
chr8_-_129469539	12.568		Tomm20	translocase of outer mitochondrial membrane 20 homolog (yeast)
chr13_+_38129095	12.546	NM_024242	Riok1	RIO kinase 1 (yeast)
chr17_+_15636851	12.534	NM_013684	Tbp	TATA box binding protein
chr10_+_57834201	12.523	NM_201242	Lims1	LIM and senescent cell antigen-like domains 1
chr2_-_172195998	12.463	NM_011497	Aurka	aurora kinase A

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.69	1.78e-116	GO:0044260	cellular macromolecule metabolic process
1.59	8.98e-99	GO:0043170	macromolecule metabolic process
1.48	3.06e-87	GO:0044237	cellular metabolic process
1.80	5.78e-78	GO:0090304	nucleic acid metabolic process
1.44	9.52e-76	GO:0044238	primary metabolic process
1.81	1.02e-75	GO:0010467	gene expression
1.70	6.41e-74	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36	1.57e-62	GO:0008152	metabolic process
1.60	1.02e-61	GO:0034641	cellular nitrogen compound metabolic process
1.58	7.67e-60	GO:0006807	nitrogen compound metabolic process
1.75	4.39e-58	GO:0016070	RNA metabolic process
1.74	3.00e-53	GO:0044267	cellular protein metabolic process
2.63	5.05e-51	GO:0006396	RNA processing
1.64	8.19e-45	GO:0009059	macromolecule biosynthetic process
1.64	2.82e-44	GO:0034645	cellular macromolecule biosynthetic process
1.55	1.33e-37	GO:0019538	protein metabolic process
2.69	1.08e-35	GO:0016071	mRNA metabolic process
2.94	1.51e-35	GO:0008380	RNA splicing
1.47	1.34e-32	GO:0044249	cellular biosynthetic process
2.79	3.15e-32	GO:0006397	mRNA processing
1.46	1.26e-31	GO:0009058	biosynthetic process
1.42	1.33e-29	GO:0060255	regulation of macromolecule metabolic process
1.69	2.03e-27	GO:0006996	organelle organization
1.52	3.11e-26	GO:0071841	cellular component organization or biogenesis at cellular level
1.39	1.84e-25	GO:0080090	regulation of primary metabolic process
2.18	6.01e-25	GO:0006259	DNA metabolic process
1.38	8.60e-25	GO:0031323	regulation of cellular metabolic process
1.35	1.24e-24	GO:0019222	regulation of metabolic process
2.58	1.26e-24	GO:0006412	translation
1.45	5.29e-24	GO:0010468	regulation of gene expression
1.42	9.00e-24	GO:0071840	cellular component organization or biogenesis
1.88	9.95e-24	GO:0007049	cell cycle
2.27	2.67e-23	GO:0006974	response to DNA damage stimulus
2.91	3.38e-23	GO:0022613	ribonucleoprotein complex biogenesis
2.85	6.19e-23	GO:0071843	cellular component biogenesis at cellular level
1.56	2.11e-22	GO:0043412	macromolecule modification
1.44	4.50e-22	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.43	3.70e-21	GO:0010556	regulation of macromolecule biosynthetic process
1.13	1.27e-20	GO:0009987	cellular process
1.41	1.36e-20	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40	3.34e-20	GO:0051171	regulation of nitrogen compound metabolic process
1.53	5.01e-19	GO:0006464	protein modification process
1.42	1.81e-18	GO:0051252	regulation of RNA metabolic process
1.45	4.75e-18	GO:0071842	cellular component organization at cellular level
1.50	4.96e-18	GO:0032774	RNA biosynthetic process
1.91	8.47e-18	GO:0022402	cell cycle process
1.49	1.91e-17	GO:0006351	transcription, DNA-dependent
2.12	3.71e-17	GO:0000278	mitotic cell cycle
2.29	5.01e-17	GO:0006281	DNA repair
1.37	5.02e-17	GO:0009889	regulation of biosynthetic process
1.41	5.32e-17	GO:0006355	regulation of transcription, DNA-dependent
1.36	6.24e-17	GO:0016043	cellular component organization
1.37	8.33e-17	GO:0031326	regulation of cellular biosynthetic process
1.96	9.11e-17	GO:0051276	chromosome organization
2.19	1.54e-16	GO:0016568	chromatin modification
1.81	7.86e-16	GO:0033554	cellular response to stress
2.41	8.48e-16	GO:0034660	ncRNA metabolic process
1.94	8.69e-16	GO:0009057	macromolecule catabolic process
2.90	2.41e-15	GO:0042254	ribosome biogenesis
1.99	7.60e-15	GO:0044265	cellular macromolecule catabolic process
1.62	8.58e-15	GO:0044085	cellular component biogenesis
2.51	1.04e-14	GO:0016570	histone modification
2.47	3.57e-14	GO:0016569	covalent chromatin modification
2.00	2.00e-13	GO:0006325	chromatin organization
2.45	7.22e-13	GO:0034470	ncRNA processing
1.87	1.60e-11	GO:0022403	cell cycle phase
2.94	5.53e-11	GO:0006364	rRNA processing
1.98	2.58e-10	GO:0030163	protein catabolic process
2.85	2.90e-10	GO:0016072	rRNA metabolic process
2.41	4.14e-10	GO:0006260	DNA replication
1.44	1.29e-09	GO:0010604	positive regulation of macromolecule metabolic process
2.00	1.79e-09	GO:0043632	modification-dependent macromolecule catabolic process
3.14	2.76e-09	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
3.14	2.76e-09	GO:0000398	nuclear mRNA splicing, via spliceosome
3.09	5.22e-09	GO:0000375	RNA splicing, via transesterification reactions
3.04	5.77e-09	GO:0071826	ribonucleoprotein complex subunit organization
1.98	7.41e-09	GO:0019941	modification-dependent protein catabolic process
1.95	1.05e-08	GO:0051603	proteolysis involved in cellular protein catabolic process
1.98	1.10e-08	GO:0006511	ubiquitin-dependent protein catabolic process
1.94	1.39e-08	GO:0044257	cellular protein catabolic process
1.72	4.22e-08	GO:0051726	regulation of cell cycle
1.39	5.06e-08	GO:0009893	positive regulation of metabolic process
1.83	8.28e-08	GO:0000279	M phase
2.03	8.60e-08	GO:0000087	M phase of mitotic cell cycle
2.97	9.13e-08	GO:0022618	ribonucleoprotein complex assembly
1.85	1.48e-07	GO:0070647	protein modification by small protein conjugation or removal
2.02	1.66e-07	GO:0000280	nuclear division
2.02	1.66e-07	GO:0007067	mitosis
1.39	1.70e-07	GO:0031325	positive regulation of cellular metabolic process
1.41	2.21e-07	GO:0033036	macromolecule localization
1.99	2.44e-07	GO:0048285	organelle fission
1.88	3.14e-07	GO:0018193	peptidyl-amino acid modification
2.61	3.63e-07	GO:0043543	protein acylation
1.45	4.17e-07	GO:0008104	protein localization
2.24	7.02e-07	GO:0010498	proteasomal protein catabolic process
2.24	7.02e-07	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
2.73	7.86e-07	GO:0006473	protein acetylation
2.85	8.30e-07	GO:0016573	histone acetylation
1.43	9.35e-07	GO:0044248	cellular catabolic process
1.78	9.67e-07	GO:0051301	cell division
1.50	1.06e-06	GO:0015031	protein transport
2.43	1.27e-06	GO:0006399	tRNA metabolic process
2.58	1.64e-06	GO:0006414	translational elongation
2.53	2.28e-06	GO:0051340	regulation of ligase activity
2.77	2.36e-06	GO:0006475	internal protein amino acid acetylation
2.77	2.36e-06	GO:0018393	internal peptidyl-lysine acetylation
1.48	2.85e-06	GO:0045184	establishment of protein localization
2.52	3.87e-06	GO:0051438	regulation of ubiquitin-protein ligase activity
2.73	3.88e-06	GO:0018394	peptidyl-lysine acetylation
2.44	4.08e-06	GO:0018205	peptidyl-lysine modification
2.60	5.14e-06	GO:0051351	positive regulation of ligase activity
1.37	6.61e-06	GO:0009056	catabolic process
2.60	8.73e-06	GO:0051443	positive regulation of ubiquitin-protein ligase activity
1.42	1.00e-05	GO:0032268	regulation of cellular protein metabolic process
1.45	1.06e-05	GO:0022607	cellular component assembly
1.53	1.07e-05	GO:0006915	apoptosis
1.84	1.13e-05	GO:0032446	protein modification by small protein conjugation
2.03	1.34e-05	GO:0006730	one-carbon metabolic process
1.53	1.51e-05	GO:0046907	intracellular transport
3.85	1.77e-05	GO:0000387	spliceosomal snRNP assembly
1.63	1.84e-05	GO:0051247	positive regulation of protein metabolic process
1.49	2.12e-05	GO:0016265	death
2.11	2.22e-05	GO:0031396	regulation of protein ubiquitination
1.24	2.46e-05	GO:0048522	positive regulation of cellular process
1.51	2.52e-05	GO:0012501	programmed cell death
1.49	2.69e-05	GO:0008219	cell death
1.74	2.88e-05	GO:0034621	cellular macromolecular complex subunit organization
2.66	2.94e-05	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.22	4.48e-05	GO:0032259	methylation
1.84	4.72e-05	GO:0016567	protein ubiquitination
1.39	5.10e-05	GO:0051641	cellular localization
1.63	6.01e-05	GO:0032270	positive regulation of cellular protein metabolic process
2.25	6.29e-05	GO:0031398	positive regulation of protein ubiquitination
1.38	6.40e-05	GO:0051246	regulation of protein metabolic process
1.49	7.69e-05	GO:0043933	macromolecular complex subunit organization
1.21	1.34e-04	GO:0048518	positive regulation of biological process
2.61	1.35e-04	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.97	1.64e-04	GO:0006368	transcription elongation from RNA polymerase II promoter
2.90	1.70e-04	GO:0006354	transcription elongation, DNA-dependent
2.27	1.71e-04	GO:0043414	macromolecule methylation
1.51	1.79e-04	GO:0071844	cellular component assembly at cellular level
2.54	1.91e-04	GO:0051352	negative regulation of ligase activity
2.54	1.91e-04	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.54	1.91e-04	GO:0051444	negative regulation of ubiquitin-protein ligase activity
1.66	2.21e-04	GO:0031401	positive regulation of protein modification process
2.36	2.23e-04	GO:0031397	negative regulation of protein ubiquitination
1.82	3.03e-04	GO:0010564	regulation of cell cycle process
2.45	3.86e-04	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.37	3.89e-04	GO:0010605	negative regulation of macromolecule metabolic process
1.72	3.96e-04	GO:0034622	cellular macromolecular complex assembly
1.49	4.56e-04	GO:0065003	macromolecular complex assembly
2.21	4.60e-04	GO:0007059	chromosome segregation
2.39	4.97e-04	GO:0006403	RNA localization
2.41	5.70e-04	GO:0050657	nucleic acid transport
2.41	5.70e-04	GO:0050658	RNA transport
2.41	5.70e-04	GO:0051236	establishment of RNA localization
1.98	6.01e-04	GO:0051052	regulation of DNA metabolic process
1.39	6.02e-04	GO:0051649	establishment of localization in cell
2.68	7.72e-04	GO:0006367	transcription initiation from RNA polymerase II promoter
2.49	8.32e-04	GO:0006352	transcription initiation, DNA-dependent
2.49	8.32e-04	GO:0010212	response to ionizing radiation
2.92	8.41e-04	GO:0000956	nuclear-transcribed mRNA catabolic process
1.99	1.09e-03	GO:0002757	immune response-activating signal transduction
2.43	1.10e-03	GO:0006479	protein methylation
2.43	1.10e-03	GO:0008213	protein alkylation
2.46	1.25e-03	GO:0051028	mRNA transport
2.68	1.32e-03	GO:0006402	mRNA catabolic process
2.79	1.44e-03	GO:0007249	I-kappaB kinase/NF-kappaB cascade
1.36	1.59e-03	GO:0002376	immune system process
1.40	1.77e-03	GO:0031399	regulation of protein modification process
2.22	2.09e-03	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.69	2.21e-03	GO:0051248	negative regulation of protein metabolic process
2.14	2.29e-03	GO:0071156	regulation of cell cycle arrest
2.48	2.39e-03	GO:0006302	double-strand break repair
1.70	2.85e-03	GO:0032269	negative regulation of cellular protein metabolic process
1.94	2.96e-03	GO:0002764	immune response-regulating signaling pathway
2.12	3.08e-03	GO:0006310	DNA recombination
1.54	3.52e-03	GO:0002684	positive regulation of immune system process
1.63	4.17e-03	GO:0030097	hemopoiesis
1.32	5.01e-03	GO:0009892	negative regulation of metabolic process
2.54	5.08e-03	GO:0006289	nucleotide-excision repair
1.86	5.20e-03	GO:0002521	leukocyte differentiation
1.84	5.26e-03	GO:0031400	negative regulation of protein modification process
1.73	5.99e-03	GO:0046649	lymphocyte activation
2.80	7.24e-03	GO:0043966	histone H3 acetylation
1.65	7.43e-03	GO:0045321	leukocyte activation
2.07	8.85e-03	GO:0051325	interphase
2.08	1.07e-02	GO:0051329	interphase of mitotic cell cycle
1.55	1.12e-02	GO:0002520	immune system development
1.56	1.18e-02	GO:0048534	hemopoietic or lymphoid organ development
2.28	1.33e-02	GO:0008033	tRNA processing
1.31	1.38e-02	GO:0006796	phosphate metabolic process
1.35	1.62e-02	GO:0016310	phosphorylation
1.31	1.62e-02	GO:0006793	phosphorus metabolic process
2.57	1.64e-02	GO:0050851	antigen receptor-mediated signaling pathway
1.24	1.68e-02	GO:0006950	response to stress
1.64	1.70e-02	GO:0010608	posttranscriptional regulation of gene expression
2.14	1.71e-02	GO:0040029	regulation of gene expression, epigenetic
1.87	1.75e-02	GO:0051251	positive regulation of lymphocyte activation
1.40	1.90e-02	GO:0002682	regulation of immune system process
2.10	1.91e-02	GO:0000075	cell cycle checkpoint
2.73	2.06e-02	GO:0006413	translational initiation
2.48	2.23e-02	GO:0051053	negative regulation of DNA metabolic process
1.31	2.35e-02	GO:0031324	negative regulation of cellular metabolic process
1.33	2.61e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.56	2.79e-02	GO:0000077	DNA damage checkpoint
1.33	3.02e-02	GO:0010628	positive regulation of gene expression
1.32	3.06e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
1.32	3.19e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.37	3.28e-02	GO:0006468	protein phosphorylation
2.81	3.67e-02	GO:0008156	negative regulation of DNA replication
2.47	3.78e-02	GO:0031570	DNA integrity checkpoint
2.47	3.78e-02	GO:0051168	nuclear export
1.34	3.83e-02	GO:0051254	positive regulation of RNA metabolic process
1.81	4.20e-02	GO:0006457	protein folding

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.35	7.47e-134	GO:0005622	intracellular
1.36	2.39e-130	GO:0044424	intracellular part
1.67	4.74e-121	GO:0005634	nucleus
1.39	3.73e-111	GO:0043226	organelle
1.39	4.98e-111	GO:0043229	intracellular organelle
1.42	3.56e-109	GO:0043227	membrane-bounded organelle
1.42	3.94e-108	GO:0043231	intracellular membrane-bounded organelle
2.08	1.18e-86	GO:0044428	nuclear part
1.55	2.65e-64	GO:0044446	intracellular organelle part
2.03	7.21e-64	GO:0031981	nuclear lumen
1.94	4.04e-63	GO:0070013	intracellular organelle lumen
1.94	8.68e-63	GO:0043233	organelle lumen
1.53	6.13e-62	GO:0044422	organelle part
1.91	1.72e-60	GO:0031974	membrane-enclosed lumen
1.55	5.30e-49	GO:0032991	macromolecular complex
1.28	3.00e-46	GO:0005737	cytoplasm
2.59	1.12e-44	GO:0030529	ribonucleoprotein complex
2.03	3.76e-43	GO:0005654	nucleoplasm
1.10	3.01e-28	GO:0005623	cell
1.10	3.01e-28	GO:0044464	cell part
1.49	3.18e-27	GO:0043228	non-membrane-bounded organelle
1.49	3.18e-27	GO:0043232	intracellular non-membrane-bounded organelle
3.30	1.29e-24	GO:0005681	spliceosomal complex
1.41	1.00e-22	GO:0043234	protein complex
2.26	3.30e-22	GO:0005730	nucleolus
1.57	5.77e-21	GO:0005829	cytosol
1.86	5.64e-20	GO:0044451	nucleoplasm part
3.42	1.50e-15	GO:0071013	catalytic step 2 spliceosome
1.93	2.73e-15	GO:0005694	chromosome
1.22	5.16e-15	GO:0044444	cytoplasmic part
2.71	2.37e-14	GO:0016604	nuclear body
2.39	8.99e-12	GO:0005840	ribosome
1.85	1.10e-11	GO:0044427	chromosomal part
1.98	3.94e-07	GO:0000228	nuclear chromosome
2.82	1.07e-06	GO:0000123	histone acetyltransferase complex
4.10	1.32e-06	GO:0005689	U12-type spliceosomal complex
2.87	1.81e-06	GO:0000502	proteasome complex
1.96	7.93e-06	GO:0044454	nuclear chromosome part
3.02	8.19e-06	GO:0022626	cytosolic ribosome
2.78	2.58e-05	GO:0016607	nuclear speck
2.17	3.47e-05	GO:0044445	cytosolic part
3.80	6.05e-05	GO:0030532	small nuclear ribonucleoprotein complex
1.88	6.47e-05	GO:0005635	nuclear envelope
2.79	7.54e-05	GO:0015935	small ribosomal subunit
3.22	9.88e-05	GO:0022627	cytosolic small ribosomal subunit
1.80	1.59e-04	GO:0000785	chromatin
2.41	4.77e-04	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
1.26	9.71e-04	GO:0005739	mitochondrion
3.42	1.23e-03	GO:0044452	nucleolar part
3.48	2.00e-03	GO:0015030	Cajal body
1.90	2.09e-03	GO:0000775	chromosome, centromeric region
1.99	3.26e-03	GO:0000151	ubiquitin ligase complex
2.03	5.56e-03	GO:0000790	nuclear chromatin
2.45	9.83e-03	GO:0016363	nuclear matrix
3.45	1.16e-02	GO:0000784	nuclear chromosome, telomeric region
3.45	1.16e-02	GO:0005839	proteasome core complex
3.91	1.21e-02	GO:0030684	preribosome
1.97	1.21e-02	GO:0000793	condensed chromosome
2.28	1.31e-02	GO:0034399	nuclear periphery
2.93	1.67e-02	GO:0000781	chromosome, telomeric region
2.49	1.90e-02	GO:0005643	nuclear pore
1.61	2.10e-02	GO:0005815	microtubule organizing center
5.47	2.25e-02	GO:0030686	90S preribosome
2.47	3.24e-02	GO:0016605	PML body
1.61	4.30e-02	GO:0005813	centrosome
3.79	4.78e-02	GO:0005852	eukaryotic translation initiation factor 3 complex

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.67	4.89e-53	GO:0003676	nucleic acid binding
2.28	4.04e-45	GO:0003723	RNA binding
1.21	6.90e-45	GO:0005488	binding
1.53	7.24e-27	GO:0000166	nucleotide binding
1.49	1.11e-18	GO:0017076	purine nucleotide binding
1.49	3.38e-18	GO:0035639	purine ribonucleoside triphosphate binding
1.48	4.49e-18	GO:0032555	purine ribonucleotide binding
1.48	5.08e-18	GO:0032553	ribonucleotide binding
1.53	1.51e-17	GO:0030554	adenyl nucleotide binding
1.23	3.75e-17	GO:0005515	protein binding
1.52	6.48e-17	GO:0032559	adenyl ribonucleotide binding
1.52	1.49e-16	GO:0005524	ATP binding
1.22	4.14e-14	GO:0003824	catalytic activity
1.43	6.16e-14	GO:0003677	DNA binding
1.36	1.34e-09	GO:0016740	transferase activity
2.43	5.84e-08	GO:0003735	structural constituent of ribosome
2.31	1.68e-07	GO:0004386	helicase activity
2.73	1.95e-07	GO:0008026	ATP-dependent helicase activity
2.73	1.95e-07	GO:0070035	purine NTP-dependent helicase activity
2.17	2.70e-07	GO:0008168	methyltransferase activity
1.36	6.22e-07	GO:0008270	zinc ion binding
2.12	9.00e-07	GO:0016741	transferase activity, transferring one-carbon groups
1.43	9.93e-07	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.67	1.62e-06	GO:0016874	ligase activity
2.41	8.06e-06	GO:0008135	translation factor activity, nucleic acid binding
1.49	3.49e-05	GO:0017111	nucleoside-triphosphatase activity
1.89	3.69e-05	GO:0019787	small conjugating protein ligase activity
1.28	4.62e-05	GO:0046914	transition metal ion binding
1.47	5.01e-05	GO:0016462	pyrophosphatase activity
1.91	5.25e-05	GO:0004842	ubiquitin-protein ligase activity
1.46	7.09e-05	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.78	7.47e-05	GO:0003712	transcription cofactor activity
1.46	7.95e-05	GO:0016817	hydrolase activity, acting on acid anhydrides
1.78	9.11e-05	GO:0000989	transcription factor binding transcription factor activity
1.75	1.63e-04	GO:0000988	protein binding transcription factor activity
1.73	2.30e-04	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.56	2.46e-04	GO:0004674	protein serine/threonine kinase activity
1.17	3.04e-04	GO:0043167	ion binding
1.77	3.08e-04	GO:0016881	acid-amino acid ligase activity
1.17	5.27e-04	GO:0046872	metal ion binding
1.17	5.81e-04	GO:0043169	cation binding
1.95	7.04e-04	GO:0003713	transcription coactivator activity
2.73	1.01e-03	GO:0004812	aminoacyl-tRNA ligase activity
2.73	1.01e-03	GO:0016875	ligase activity, forming carbon-oxygen bonds
2.73	1.01e-03	GO:0016876	ligase activity, forming aminoacyl-tRNA and related compounds
2.50	1.13e-03	GO:0003743	translation initiation factor activity
2.58	1.39e-03	GO:0004527	exonuclease activity
1.36	1.74e-03	GO:0016301	kinase activity
1.72	1.78e-03	GO:0042623	ATPase activity, coupled
1.90	2.24e-03	GO:0004518	nuclease activity
1.34	2.85e-03	GO:0019899	enzyme binding
1.63	3.63e-03	GO:0016887	ATPase activity
2.03	3.80e-03	GO:0016779	nucleotidyltransferase activity
1.56	6.57e-03	GO:0008134	transcription factor binding
2.67	8.26e-03	GO:0003684	damaged DNA binding
3.38	1.14e-02	GO:0004298	threonine-type endopeptidase activity
3.38	1.14e-02	GO:0070003	threonine-type peptidase activity
1.19	1.15e-02	GO:0016787	hydrolase activity
2.16	1.21e-02	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
1.39	1.27e-02	GO:0004672	protein kinase activity
1.36	1.36e-02	GO:0016773	phosphotransferase activity, alcohol group as acceptor
3.23	2.32e-02	GO:0000049	tRNA binding
2.93	2.71e-02	GO:0003678	DNA helicase activity
4.78	4.47e-02	GO:0070577	histone acetyl-lysine binding
1.43	4.79e-02	GO:0060589	nucleoside-triphosphatase regulator activity